BoLA-DRB3 polymorphism controls proviral load and infectivity of bovine leukemia virus (BLV) in milk

Nakatsuchi A, Watanuki S, Borjigin L, Sato H, Bai L, Matsuura R, Kuroda M, Murakami H, Sato R, Asaji S, Ando A, Matsumoto Y, Takeshima SN, Aida Y.

The visualization of infectivity of milk cells using a luminescence syncytium induction assay showed that the infectious risk of milk from BLV-infected dams was markedly high for susceptible dams compared to resistant ones. This is the first report confirming that BoLA-DRB3 polymorphism affects the PVL and infectivity of milk from BLV-infected dams.

Pathogens,

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