Proventricular Dilatation Disease Associated with Avian Bornavirus Infection in a Citron-Crested Cockatoo that Was Born and Hand-Reared in Japan

Hirohito Ogawa
Yasuyuki Sanada
Naoko Sanada
Megumi Kudo
Kotaro Tuchiya
Toshiaki Kodama
Koji Uetsuka

A 5-month-old female Citron-crested Cockatoo (Cacatua sulphurea citrinocristata) that was born and hand-reared in Japan died with suspected proventricular dilatation disease (PDD). Macroscopic and microscopic examinations of the bird revealed characteristic features of PDD, i.e., distention of the proventriculus and infiltration of lymphocytes and plasma cells in ganglia of various organs and in central and peripheral nerves. A linkage of this PDD case to infection with avian bornavirus (ABV) was documented by RTPCR amplification of the virus genomes from the affected bird. Phylogenetic analysis revealed that the ABV identified in this study clustered into the genotype 2, which is one of the dominant ABV genotypes worldwide. To the best of our knowledge, this is the first report of a natural case of PDD associated with ABV infection in Japan.

JOURNAL OF VETERINARY MEDICAL SCIENCE

JAPAN SOC VET SCI

73

6

837

840

10.1292/jvms.10-0465

https://doi.org/10.1292/jvms.10-0465
https://www.ncbi.nlm.nih.gov/pubmed/21289471
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