Academic Thesis

Basic information

Name Kojima Isshu
Belonging department
Occupation name
researchmap researcher code R000055330
researchmap agency Okayama University of Science

Title 

A Lethal Case of Natural Infection with the H5N8 Highly Pathogenic Avian Influenza Virus of Clade 2.3.4.4 in a Mandarin Duck

					

					

						

							

								

									
Bibliography　Type 

									
								

							

						

						
Joint Author

					

					

						

							

								

									
Author 

									
								

							

						

						
Ahmed Magdy Khalil/Hitoshi Hatai/Yoshikazu Fujimoto/Isshu Kojima/Misuzu Okajima/Mana Esaki/Kyonha Kinoshita/Makoto Ozawa

					

					

						

							

								

									
Summary 

									
								

							

						

						
Recent global outbreaks of highly pathogenic avian influenza viruses (HPAIVs) of the H5N8 subtype in poultry and wild birds have raised concerns about animal and human health, particularly after its first evidence of zoonotic transmission from birds to humans. Here, we report a lethal infection with the H5N8 HPAIV in a mandarin duck that had previously demonstrated resistance to the H5N8 HPAIV infection. In addition, we revealed that the isolated virus was a genetic reassortant between the existing H5N8 HPAIV and LPAIV(s). Although further studies are warranted to assess the impact of the genetic reassortment on virus pathogenicity, the potential role of mandarin ducks in HPAIV dissemination should be re-evaluated.

					

					

						

							

								

									
Magazine(name) 

									
								

							

						

						
Zoonotic Diseases

					

					

						

							

								

									
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MDPI AG

					

					

						

							

								

									
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2

					

					

						

							

								

									
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1

					

					

						

							

								

									
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32

					

					

						

							

								

									
EndingPage 

									
								

							

						

						
36

					

					

						

							

								

									
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2022/03

					

					

						

							

								

									
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Research papers (academic journals)

					

					

						

							

								

									
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DOI 

									
								

							

						

						
10.3390/zoonoticdis2010004

					

					

						

							

								

									
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