Academic Thesis

Basic information

Name Katayama Keiichi
Belonging department
Occupation name
researchmap researcher code B000305947
researchmap agency Okayama University of Science

Title

Apoptosis in the developing mouse embryos from T-2 toxin-inoculated dams

Bibliography Type

 

Author

N Ishigami
J Shinozuka
K Katayama
K Uetsuka
H Nakayama
K Doi

Summary

T-2 toxin (3mg/kg b.w.) was orally inoculated to pregnant mice at 11 days of gestation to examine the effect of T-2 toxin on the developing embryos. At 24 hours after T-2 toxin-inoculation, moderate pyknosis or karyorrhexis was generally observed in some layers of the central nervous system, caudal sclerotomic segment, caudal region of the tongue to pharyngeal- to laryngeal-mesenchyma, trachea and facial mesenchyma. These pyknotic or karyorrhectic nuclei were strongly stained by the modified TUNEL method widely used for the in situ detection of apoptotic nuclei and also showed ultrastructural changes characteristic for apoptosis. This is the first report of mycotoxin-induced apoptosis in embryos.

Magazine(name)

HISTOLOGY AND HISTOPATHOLOGY

Publisher

F HERNANDEZ

Volume

14

Number Of Pages

3

StartingPage

729

EndingPage

733

Date of Issue

1999-07

Referee

Exist

Invited

Not exist

Language

English

Thesis Type

Research papers (academic journals)

ISSN

 

DOI

 

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PMID

 

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arXiv ID

 

ORCID Put Code

 

DBLP ID