Cell culture in a closed nano-space

T Doi
S Matsunaga
E Maeno
K Tsuchiya
T Higashi
S Misawa
S Uchiyama
T Ooi
M Nakao
K Fukui

The minimum size of a closed nano-space in which cells can survive was determined using 4-nl nanowells. One or two cells could divide in the nanowell. Our results suggest that the cell division activity in the nano-space is determined by the conflict between intercellular effects and consumption of substrates.

JOURNAL OF BIOSCIENCE AND BIOENGINEERING

SOC BIOSCIENCE BIOENGINEERING JAPAN

98

4

304

305

10.1263/jbb.98.304

https://doi.org/10.1263/jbb.98.304
http://ci.nii.ac.jp/naid/110002665379
https://www.ncbi.nlm.nih.gov/pubmed/16233710
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000225898200013&DestApp=WOS_CPL