Synthesis of glycosides of resveratrol, pinostilbene, and piceatannol by bioconversion with Phytolacca americana

Kei Shimoda, Naoji Kubota, Daisuke Uesugi, Yuya Fujitaka, Shouta Doi, Hiroki Hamada, Atsuhito Kuboki, Yuya Kiriake, Takafumi Iwaki, Tomohiro Saikawa, Shin-ichi Ozaki

Cultured cells of Phytolacca americana, which had been cultivated in the dark, biotransformed resveratrol to pinostilbene and pterostilbene 4'-O-β-d-glucoside, together with the 3- and 4'-O-β-D-glucosides of resveratrol. Pinostilbene was converted into its 3-O-β-d-glucoside and pterostilbene. In addition, the cells transformed piceatannol to its 4'-O-β-d-glucoside, isorhapontigenin, and isorhapontigenin 3-O-β-D-glucoside. 

Natural Product Communications

Sage Journals

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