[Satoko Sugimoto,Shingo Maeda,Masaya Tsuboi,Kohei Saeki,James K Chambers,Tomohiro Yonezawa,Kenjiro Fukushima,Reina Fujiwara,Kazuyuki Uchida,Hajime Tsujimoto,Naoaki Matsuki,Koichi Ohno]
A 6-year 5-month-old spayed female Scottish Fold cat presented with a one-month history of gait abnormalities, increased salivation, and decreased activity. A blood test showed hyperammonemia and increased serum bile acids. Imaging tests revealed multiple shunt vessels indicating acquired portosystemic shunt. Histopathologic analysis of liver biopsy showed features consistent with liver hypoperfusion, such as a barely recognizable portal vein, increased numbers of small arterioles, and diffuse vacuolar degeneration of hepatocytes. These findings supported the diagnosis of primary hypoplasia of the portal vein/microvascular dysplasia, (PHPV/MVD). To our knowledge, this is the first case of feline PHPV/MVD that developed multiple acquired portosystemic shunts and presented with hepatic encephalopathy.
Research papers (academic journals)
