Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex.

Shuichi Chiba, Tadahiro Numakawa, Midori Ninomiya, Misty C Richards, Chisato Wakabayashi, Hiroshi Kunugi

Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex.

Prog Neuropsychopharmacol Biol Psychiatry

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