Bimodal immunoglobulin A gammopathy in a cat with feline myeloma-related disorders

Masaya Igase
Takako Shimokawa Miyama
Satoshi Kambayashi
Yumiko Shimoyama
Hiroko Hiraoka
Yumi Hirata
Miki Iwata
Kenji Baba
Takuya Mizuno
Masaru Okuda

A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb was revealed with bimodal monoclonal gammopathy composed of IgA by immunoelectrophoresis and immunofixation. Approximately 1 month after referral, the cat died due to renal failure. Postmortem immunohistopathologic evaluation of the subcutaneous mass revealed neoplastic cell proliferation of plasma cells and giant myeloma cells. Neoplastic cells were also present in the liver and spleen. These results led to the diagnosis of a rare case of feline myeloma-related disorders with extramedullary plasmacytoma infiltrating in multiple locations. This report emphasizes the necessity to accumulate cases with similar clinicopathologic findings in the future.

JOURNAL OF VETERINARY MEDICAL SCIENCE

JAPAN SOC VET SCI

78

4

691

695

10.1292/jvms.15-0156

https://doi.org/10.1292/jvms.15-0156
https://www.ncbi.nlm.nih.gov/pubmed/26638898
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873863
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