A dog with myelodysplastic syndrome: Chronic myelomonocytic leukemia

Hiroko Hiraoka
Masaharu Hisasue
Naho Nagashima
Takako Miyama
Takashi Tanimoto
Malaika Watanabe
Kazuhito Itamoto
Takuya Mizuno
Hisashi Inokuma
Masaru Okuda

An eleven-year-old female pug was referred to Yamaguchi University Animal Hospital for evaluation of anemia and thrombocytopenia. The cytological examination of the peripheral blood showed some giant monocytic lineage blast cells. A few granulocytes and platelets had dysplastic features. On day 7, in addition to increasing the monocytic lineage cells, the dysplastic features of the blood had also increased compared to the initial examination. We performed bone marrow aspiration upon her death. The bone marrow revealed dysplastic features in all three hematopoietic cell lines, and an increase in the monocytic cell line. Based on the features of the bone marrow and the peripheral blood, this case was confirmed to be myelodysplastic syndrome-Chronic myelomonocytic leukaemia (MDS-CMML).

JOURNAL OF VETERINARY MEDICAL SCIENCE

JAPAN SOC VET SCI

69

6

665

668

10.1292/jvms.69.665

https://doi.org/10.1292/jvms.69.665
https://www.ncbi.nlm.nih.gov/pubmed/17611368
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