Clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50

Miyama, Takako
Inokuma, Hisashi
Itamoto, Kazuhito
Okuda, Masaru
Verdida, Rodolfo A.
Xuan, Xuenan

The clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50 was examined in dogs in an area where B. gibsoni infection was endemic. Only 8 among 14 dogs with acute type B. gibsoni infection without a previous history of infection were positive. This high percentage of false-negative results is thought to be a weak point of ELISA as a diagnostic tool. However, 14 other anemic dogs with a confirmed history of B. gibsoni infection were all positive, thus confirming the higher sensitivity of ELISA in detecting a history of infection.

JOURNAL OF VETERINARY MEDICAL SCIENCE

JAPAN SOC VET SCI

68

12

1371

1373

10.1292/jvms.68.1371

https://doi.org/10.1292/jvms.68.1371
https://www.ncbi.nlm.nih.gov/pubmed/17213713
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