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| 基本情報 |
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| 氏名 |
池田 正五 |
| 氏名（カナ） |
ｲｹﾀﾞ ｼﾖｳｺﾞ |
| 氏名（英語） |
Ikeda Shiyogo |
| 所属 |
生命科学部 生物科学科 |
| 職名 |
教授 |
| researchmap研究者コード |
1000113908 |
| researchmap機関 |
岡山理科大学 |
Nepalensinols D-G, New Resveratrol Oligomers from Kobresia nepalensis (Cyperaceae) as Potent Inhibitors of DNA Topoisomerase II.
Yamada M, Hayashi K, Hayashi H, Tsuji R, Kakumoto K, Ikeda S, Hoshino T, Tsutsui K, Tsutsui K, Ito T, Iinuma M, and Nozaki H.
Four new resveratrol oligomers, nepalensinols D-G, were isolated from the stem of Kobresia nepalensis (Cyperaceae). The structures were determined by detailed NMR spectral analysis. The compounds were assessed for their inhibitory activity against human topoisomerase II, a potential target of anti-tumor agents. These stilbenoids showed potent inhibitory activity against human topoisomerase II with IC(50) values of 5-15 muM.
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