|
|
基本情報 |
|
氏名 |
窪木 厚人 |
氏名(カナ) |
クボキ アツヒト |
氏名(英語) |
Kuboki Atsuhito |
所属 |
生命科学部 生物科学科 |
職名 |
准教授 |
researchmap研究者コード |
1000311530 |
researchmap機関 |
岡山理科大学 |
Total synthesis of cleomiscosin C via a regioselective cycloaddition reaction of o-quinone
A. Kuboki, C. Maeda, T. Arishige, K. Kuyama, M. Hamabata, S. Ohira
We have achieved total synthesis of cleomiscosin C (aquillochin) (I) through regioselective cycloaddition of o-quinone II and protected sinapyl alc. III as a key step. During preparation of the o-quinone from phenol by IBX oxidation, silyl substituents adjacent to the phenolic hydroxyl group afforded effective inhibition of an undesired oxidative elimination.
|