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| 基本情報 |
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| 氏名 |
窪木 厚人 |
| 氏名（カナ） |
ｸﾎﾞｷ ｱﾂﾋﾄ |
| 氏名（英語） |
Kuboki Atsuhito |
| 所属 |
生命科学部 生物科学科 |
| 職名 |
准教授 |
| researchmap研究者コード |
1000311530 |
| researchmap機関 |
岡山理科大学 |
New naphthoquinone and monoterpenoid from Plumbago zeylanica
Ohira, Susumu; Yokogawa, Yoshiaki; Tsuji, Shinji; Mitsui, Taichi; Fukukawa, Tatsuhiko; Hayashi, Ken-ichiro; Kuboki, Atsuhito; Matsuura, Nobuyasu; Iinuma, Munekazu; Nozaki, Hiroshi
A new naphthoquinone (I) and new monoterpenoid (II) were isolated from the stems of Plumbago zeylanica, and their structures were determined on the basis of 2D NMR spectroscopy. The absolute configuration of II was established by synthesis of its enantiomer. I exhibited potent inhibitory activity against nuclear factor κB (NF-κB), equivalent to that of parthenolide, a known potent inhibitor of NF-κB.
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