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| 基本情報 |
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| 氏名 |
窪木 厚人 |
| 氏名（カナ） |
ｸﾎﾞｷ ｱﾂﾋﾄ |
| 氏名（英語） |
Kuboki Atsuhito |
| 所属 |
生命科学部 生物科学科 |
| 職名 |
准教授 |
| researchmap研究者コード |
1000311530 |
| researchmap機関 |
岡山理科大学 |
Stereoselective synthesis of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid via C-H insertion of alkylidenecarbene.
Ohira, Susumu; Akiyama, Megumi; Kamihara, Kumiko; Isoda, Yuichi; Kuboki, Atsuhito.
The aminocyclitol moiety of (+)-trehazolin, a powerful trehalase inhibitor, was synthesized in a stereocontrolled manner from cis-2-butene-1,4-diol via C-H insertion reaction of the alkylidenecarbene, followed by regioselective opening of the epoxide ring. It was obtained in an enantiomerically pure form by twice using Sharpless asym. epoxidation.
Bioscience, Biotechnology, and Biochemistry
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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