Replacing alkyl sulfonamide with aromatic sulfonamide in sulfonamide-type RXR agonists favors switch towards antagonist activity

By Morishita, Ken-ichi; Yakushiji, Nobumasa; Ohsawa, Fuminori; Takamatsu, Kayo; Matsuura, Nobuyasu; Makishima, Makoto; Kawahata, Masatoshi; Yamaguchi, Kentaro; Tai, Akihiro; Sasaki, Kenji; Kakuta, Hiroki

alkyl sulfonamide

Bioorg. Med. Chem. Lett.

19

3

1001

1003