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| 基本情報 |
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| 氏名 |
松浦 信康 |
| 氏名（カナ） |
ﾏﾂｳﾗ ﾉﾌﾞﾔｽ |
| 氏名（英語） |
Matsura Nobuyasu |
| 所属 |
生命科学部 生物科学科 |
| 職名 |
教授 |
| researchmap研究者コード |
R000014159 |
| researchmap機関 |
岡山理科大学 |
Cryptoic acids A and B, benzene-containing polyketides, and cyclocryptamide, a modified diketopiperazine, from an actinomycete of the genus Cryptosporangium
Md Julkar Nime 1, Hideki Yamamura 2, Masayuki Hayakawa 3, Nobuyasu Matsuura 4, Naoya Oku 1, Yasuhiro Igarashi 5
Two new benzene-containing polyketides, cryptoic acids A (1) and B (2), along with a new acylated diketopiperazine designated cyclocryptamide (3), were isolated from the culture extract of Cryptosporangium sp. YDKA-T02. The absolute configuration of amino acid components in 3 was determined by Marfey's method. While 3 was not cytotoxic and inactive against microbial test strains, 1 and 2 showed PPARγ agonistic activity in a reporter gene assay and cytotoxicity against P388 murine leukemia cells.
10.1038/s41429-024-00794-4
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