Titanium alloys containing beta-stabilizing elements have several superior properties when compared to other conventional metals. However, there is a lack of knowledge about the mechanical behavior of titanium alloys especially under biaxial compressive stress conditions, which are important for the application of compressive metal-forming processes such as forging and extrusion. In addition, the primary plastic deformation mechanism also changes with the amount of β-stabilizing elements, and their influences on mechanical properties are not fully understood. In this report, uniaxial compression and biaxial compressions along linear strain paths were performed on binary metastable β-titanium alloys (Ti-Mo and Ti-Nb alloys). The compressive deformation behavior is investigated and summarized for the influence of the amount of the β-stabilizing element. The quantitative expression of the stress-strain relationship with respect to the amount of beta-stabilizer elements has also been discussed.