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基本情報
| 氏名 |
神吉 けい太 |
| 氏名（カナ） |
ｶﾝｷ ｹｲﾀ |
| 氏名（英語） |
Kanki Keita |
| 所属 |
生命科学部 生物科学科 |
| 職名 |
教授 |
| researchmap研究者コード |
R000012780 |
| researchmap機関 |
岡山理科大学 |
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- 2021/07 有尾両生類にみるがんの更生プログラム 神吉けい太 生物工学
- 2021/01 Glycolytic inhibition by resveratrol prevents myoblast cell death caused by glucose deprivation and hypoxia; a possible application to the three-dimensional tissue construction. Naito K, Kanki K. Journal of bioscience and bioengineering.
- 2021/01 Liver-specific dysregulation of clock-controlled output signal impairs energy metabolism in liver and muscle. Matsumura T, Ohta Y, Taguchi A, Hiroshige S, Kajimura Y, Fukuda N, Yamamoto K, Nakabayashi H, Fujimoto R, Yanai A, Shinoda K, Watanabe K, Mizukami Y, Kanki K, Shiota G, Tanizawa Y. 共著 Biochemical and biophysical research communications.
- 2020/09 HDAC9 Is Preferentially Expressed in Dedifferentiated Hepatocellular Carcinoma Cells and Is Involved in an Anchorage-Independent Growth. Kanki K, Watanabe R, Nguyen Thai L, Zhao CH, Naito K. Cancers (Basel)
- 2020/04 Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling. Harada K, Ohashi R, Naito K, Kanki K. 共著
International journal of molecular sciences
- 2019/02 細胞内エネルギー代謝シフトを利用した細胞分化促進技術の検討 神吉けい太 単著 岡山理科大学技術科学研究所年報
- 2018/05 Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid. Qin XY, Suzuki H, Honda M, Okada H, Kaneko S, Inoue I, Ebisui E, Hashimoto K, Carninci P, Kanki K, Tatsukawa H, Ishibashi N, Masaki T, Matsuura T, Kagechika H, Toriguchi K, Hatano E, Shirakami Y, Shiota G, Shimizu M, Moriwaki H, Kojima S. 共著 Proceedings of the National Academy of Sciences U S A.
- 2017/03 All-trans retinoic acid ameliorates hepatic stellate cell activation via suppression of thioredoxin interacting protein expression. Shimizu H, Tsubota T, Kanki K, Shiota G. J Cell Physiol.
- 2017/03 Impact of Preferentially Expressed Antigen of Melanoma on the Prognosis of Hepatocellular Carcinoma. Oyama K, Kanki K, Shimizu H, Kono Y, Azumi J, Toriguchi K, Hatano E, Shiota G. Gastrointest Tumors.
- 2016/06 Wnt/Beta-Catenin Signal Inhibitor HC-1 Sensitizes Oral Squamous Cell Carcinoma Cells to 5-Fluorouracil through Reduction of CD44-Positive Population. Yokogi S, Tsubota T, Kanki K, Azumi J, Itaba N, Oka H, Morimoto M, Ryoke K, Shiota G. Yonago Acta Med.
- 2016/02 Liver Resident Macrophages (Kupffer Cells) Share Several Functional Antigens in Common with Endothelial Cells. Okada T, Kimura A, Kanki K, Nakatani S, Nagahara Y, Hiraga M, Watanabe Y. Scandinavian Journal of Immunology
- 2015/11/Identification of the small molecule compound which induces hepatic differentiation of human mesenchymal stem cells./Itaba N, Sakabe T, Kanki K, Azumi J, Shimizu H, Kono Y, Matsumi Y, Abe KI, Tonoi T, Oka H, Sakurai T, Saimoto H, Morimoto M, Mabuchi Y, Matsuzaki Y, Shiota G/Joint Author/Regenerative Therapy
- 2015/08 Involvement of glucocorticoid in induction of lingual T1R3 in rodents. Ogawa N, Kanki K, Honda K, Tomooka Y, Ryoke K, Watanabe T. European Journal of Pharmacology
- 2015/02 Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib. Ishijima N, Kanki K, Shimizu H, Shiota G. Cancer Science
- 2014/06 In-silico解析に基づいたレチノイン酸応答性遺伝子の同定と肝細胞癌の分子標的探索 神吉けい太、汐田剛史 医学のあゆみ
- 2014/03 肝細胞癌治療の標的分子探索を目指したレチノイン酸応答性遺伝子の解析 神吉けい太、汐田剛史 肝胆膵
- 2013/11 Biological and clinical implications of retinoic acid-responsive genes in human hepatocellular carcinoma cells. Kanki K, Akechi Y, Ueda C, Tsuchiya H, Shimizu H, Ishijima N, Toriguchi K, Hatano E, Endo K, Hirooka Y, Shiota G. Journal of Hepatology
- 2013/08 Retinoids and their target genes in liver functions and diseases. Shiota G, Kanki K. Journal of Gastroenterology and Hepatology
- 2013/07 肝細胞癌におけるレチノイド応答性遺伝子の生物学的・臨床的意義 神吉けい太、汐田剛史 ゲノム情報の臨床応用
- 2013/02 Identification of the genes chemosensitizing hepatocellular carcinoma cells to interferon-α/5-fluorouracil and their clinical significance. Sakabe T, Tsuchiya H, Kanki K, Azumi J, Gonda K, Mizuta Y, Yamada D, Wada H, Shomori K, Nagano H, Shiota G. 共著 PLoS One.
- 2012/11 Genome-wide identification of retinoic acid-responsive genes by a novel screening strategy and mRNA expression and functional analysis of the genes in human hepatocellular carcinoma. Kanki K, Hatano E, Endo K, Hirooka Y, Shiota G 共著 The 10th JSH single topic conference “Hepatitis C: Best practice based on science”
- 2012/07 肝細胞癌治療の標的分子探索としてのレチノイン酸応答遺伝子の解析 神吉けい太、汐田剛史 分子生物学が可能とした個別化医療
- 2012/03 The nucleocapsid protein of measles virus blocks host interferon response. Takayama I, Sato H, Watanabe A, Omi-Furutani M, Sugai A, Kanki K, Yoneda M, Kai C. Virology
- 2011/03 Disrupted plasma membrane localization of equilibrative nucleoside transporter 2 in the chemoresistance of human pancreatic cells to gemcitabine (dFdCyd). Nishio R, Tsuchiya H, Yasui T, Matsuura S, Kanki K, Kurimasa A, Hisatome I, Shiota G. 共著 Cancer Science
- 2011/03 c-Jun N-terminal kinase activation by oxidative stress suppresses retinoid signaling through proteasomal degradation of retinoic acid receptor α protein in hepatic cells. Hoshikawa Y, Kanki K, Ashla AA, Arakaki Y, Azumi J, Yasui T, Tezuka Y, Matsumi Y, Tsuchiya H, Kurimasa A, Hisatome I, Hirano T, Fujimoto J, Kagechika H, Shomori K, Ito H, Shiota G. 共著 Cancer Science
- 2010/12 Iron state in association with retinoid metabolism in non-alcoholic fatty liver disease. Tsuchiya H, Ashla AA, Hoshikawa Y, Matsumi Y, Kanki K, Enjoji M, Momosaki S, Nakamuta M, Taketomi A, Maehara Y, Shomori K, Kurimasa A, Hisatome I, Ito H, Shiota G. 共著 Hepatology Research
- 2009/11 Preparation of an artificial cell cycle progressor with a novel mechanism. Kanki K, Ishijima Y, Watanabe Y. Biological & pharmaceutical bulletin
- 2009/03 Control of ER stress by a chemical chaperone counteracts apoptotic signals in IFN-gamma-treated murine hepatocytes. Kanki K, Kawamura T, Watanabe Y. 共著 Apoptosis
- 2008/02 A possible role of nrf2 in prevention of renal oxidative damage by ferric nitrilotriacetate. Kanki K, Umemura T, Kitamura Y, Ishii Y, Kuroiwa Y, Kodama Y, Itoh K, Yamamoto M, Nishikawa A, Hirose M. 共著 Toxicologic Pathology
- 2008/01 Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation. Kuroiwa Y, Okamura T, Ishii Y, Umemura T, Tasaki M, Kanki K, Mitsumori K, Hirose M, Nishikawa A. 共著 Cancer Science
- 2007/07 Combined treatment with green tea catechins and sodium nitrite selectively promotes rat forestomach carcinogenesis after initiation with N-methyl-N'- nitro-N-nitrosoguanidine. Kuroiwa Y, Ishii Y, Umemura T, Kanki K, Mitsumori K, Nishikawa A, Nakazawa H, Hirose M. Cancer Science
- 2007/01 Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo[4,5-f]quinoline. Kitamura Y, Umemura T, Kanki K, Kodama Y, Kitamoto S, Saito K, Itoh K, Yamamoto M, Masegi T, Nishikawa A, Hirose M. 共著 Cancer Science
- 2007/01 Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice. Kuroiwa Y, Umemura T, Nishikawa A, Kanki K, Ishii Y, Kodama Y, Masumura K, Nohmi T, Hirose M. 共著 Archives of toxicology
- 2006/09 In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate. Umemura T, Kanki K, Kuroiwa Y, Ishii Y, Okano K, Nohmi T, Nishikawa A, Hirose M. 共著 Cancer Science
- 2006/09 Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters. Kuroiwa Y, Nishikawa A, Kitamura Y, Kanki K, Ishii Y, Umemura T, Hirose M. Cancer Letters
- 2006/05 Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine. Kitamura Y, Umemura T, Okazaki K, Kanki K, Imazawa T, Masegi T, Nishikawa A, Hirose M. 共著 International Journal of Cancer
- 2006/05 Lung as a new target in rats of 2-amino-3-methylimidazo[4,5-f]quinoline carcinogenesis: results of a two-stage model initiated with N-bis(2-hydroxypropyl)nitrosamine. Kitamura Y, Umemura T, Kanki K, Ishii Y, Kuroiwa Y, Masegi T, Nishikawa A, Hirose M. Cancer Science
- 2006/03 A crucial role of Nrf2 in in vivo defense against oxidative damage by an environmental pollutant, pentachlorophenol. Umemura T, Kuroiwa Y, Kitamura Y, Ishii Y, Kanki K, Kodama Y, Itoh K, Yamamoto M, Nishikawa A, Hirose M. Toxicological Sciences
- 2006/03 Possible involvement of NO-mediated oxidative stress in induction of rat forestomach damage and cell proliferation by combined treatment with catechol and sodium nitrite. Ishii Y, Umemura T, Kanki K, Kuroiwa Y, Nishikawa A, Ito R, Saito K, Nakazawa H, Hirose M. Archives of biochemistry and biophysics
- 2006/01 A subchronic toxicity study of dunaliella carotene in F344 rats. Kuroiwa Y, Nishikawa A, Imazawa T, Kitamura Y, Kanki K, Ishii Y, Umemura T, Hirose M. Food and chemical toxicology
- 2006/01 MX, a by-product of water chlorination, lacks in vivo genotoxicity in gpt delta mice but inhibits gap junctional intercellular communication in rat WB cells. Nishikawa A, Sai K, Okazaki K, Son HY, Kanki K, Nakajima M, Kinae N, Nohmi T, Trosko JE, Inoue T, Hirose M. Environmental and molecular mutagenesis
- 2006/01 Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model. Umemura T, Kodama Y, Nishikawa A, Hioki K, Nomura T, Kanki K, Kuroiwa Y, Ishii Y, Kurokawa Y, Hirose M. Cancer Letters
- 2005/09 Lack of carcinogenicity of D-xylose given in the diet to F344 rats for two years. Kuroiwa Y, Nishikawa A, Imazawa T, Kitamura Y, Kanki K, Umemura T, Hirose M. Food and chemical toxicology
- 2005/07 Lack of subchronic toxicity of an aqueous extract of Agaricus blazei Murrill in F344 rats. Kuroiwa Y, Nishikawa A, Imazawa T, Kanki K, Kitamura Y, Umemura T, Hirose M. Food and Chemical Toxicology
- 2005/04 Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment. Nishikawa A, Imazawa T, Kuroiwa Y, Kitamura Y, Kanki K, Ishii Y, Umemura T, Hirose M. Toxicological Sciences
- 2005/01 In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2-ethylhexyl)phthalate. Kanki K, Nishikawa A, Masumura K, Umemura T, Imazawa T, Kitamura Y, Nohmi T, Hirose M. Molecular Carcinogenesis 2005 Jan;42(1):9-17. doi: 10.1002/mc.20061.
- 2004/05 Dose-related changes of oxidative stress and cell proliferation in kidneys of male and female F344 rats exposed to potassium bromate. Umemura T, Kitamura Y, Kanki K, Maruyama S, Okazaki K, Imazawa T, Nishimura T, Hasegawa R, Nishikawa A, Hirose M. Cancer Science
- 2004/03 Specificity of co-promoting effects of caffeine on thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine. Son HY, Nishikawa A, Okazaki K, Kitamura Y, Kanki K, Lee KY, Umemura T, Hirose M. Toxicologic Pathology
- 2003/11 Low dose genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in gpt delta transgenic mice. Masumura K, Horiguchi M, Nishikawa A, Umemura T, Kanki K, Kanke Y, Nohmi T. Mutation Research
- 2003/10 A 13-week subchronic toxicity study of paprika color in F344 rats. Kanki K, Nishikawa A, Furukawa F, Kitamura Y, Imazawa T, Umemura T, Hirose M. Food and Chemical Toxicology
- 2003/06 Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion. Umemura T, Kai S, Hasegawa R, Kanki K, Kitamura Y, Nishikawa A, Hirose M. Carcinogenesis
- 2003/04 A cyclooxygenase-2 inhibitor, nimesulide, inhibits postinitiation phase of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters. Furukawa F, Nishikawa A, Lee IS, Kanki K, Umemura T, Okazaki K, Kawamori T, Wakabayashi K, Hirose M. International Journal of Cancer
- 2003/04 Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine. Son HY, Nishikawa A, Kanki K, Okazaki K, Kitamura Y, Lee KY, Umemura T, Hirose M. Cancer Science
- 2003/02 Prolonged effects of beta-estradiol 3-benzoate on thyroid tumorigenesis in gonadectomized rats pretreated with N-bis(2-hydroxypropyl)nitrosamine. Son HY, Nishikawa A, Okazaki K, Kanki K, Yamagishi M, Imazawa T, Umemura T, Hirose M. Cancer Letters
- 2003/01 Pentachlorophenol (but not phenobarbital) promotes intrahepatic biliary cysts induced by diethylnitrosamine to cholangio cystic neoplasms in B6C3F1 mice possibly due to oxidative stress. Umemura T, Kodama Y, Kanki K, Iatropoulos MJ, Nishikawa A, Hirose M, Williams GM. Toxicologic Pathology
- 2002/03 有尾両生類における変態と生殖腺の内分泌学的研究 神吉けい太 単著 北海道大学大学院理学研究科（博士論文）
- 2001/12 Differentiation behavior of pituitary cells in normal and metamorphosis-arrested larvae of the salamander Hynobius retardatus. Furuta K, Kanki K, Wakahara M. International Journal of Developmental Biology
- 2000/09 Spatio-temporal expression of TSH beta and FSH beta genes in normally metamorphosing, metamorphosed, and metamorphosis-arrested Hynobius retardatus. Kanki K, Wakahara M. General and Comparative Endocrinology
- 1999/05 Precocious testicular growth in metamorphosis-arrested larvae of a salamander Hynobius retardatus: role of thyroid-stimulating hormone. Kanki K, Wakahara M. The Journal of experimental zoology
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