Competitive research funds

Basic information

Name Inoue Takashi
Belonging department
Occupation name
researchmap researcher code B000003480
researchmap agency Okayama University of Science

Title 

Assessment of fecal microbiota transplantation therapy using spontaneous disease models of common marmosets

					

					

						

							

								

									
Provider 

									
								

							

						

						
Japan Society for the Promotion of Science

					

					

						

							

								

									
System 

									
								

							

						

						
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)

					

					

						

							

								

									
From Date 

									
								

							

						

						
2016-04-01

					

					

						

							

								

									
To Date 

									
								

							

						

						
2018-03-31

					

					

						

							

								

									
OwnerRole 

									
								

							

						

						
 

					

					

						

							

								

									
Author 

									
								

							

						

						
INOUE Takashi
NOZU Ryoko
SATO Kenya
SASAKI Emi

					

					

						

							

								

									
Category 

									
								

							

						

						
Grant-in-Aid for Young Scientists (B)

					

					

						

							

								

									
Summary 

									
								

							

						

						
Therapeutic effect of fecal microbiota transplantation (FMT) was assessed using common marmosets as a nonhuman primate model. FMT therapy resulted in ameliorating diarrhea, weight loss, hypoalbuminemia and anemia in some chronic diarrhea cases of marmosets. FMT also tended to cure recurrent Clostridium difficile infection in marmosets. Analysis of fecal bacterial flora based on the 16S rRNA gene showed shifts of bacterial composition in the animals after FMT, implying that FMT therapy cured dysbiosis related to these intestinal diseases.