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MISC
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Basic information
Name
Koga Yuuichi
Belonging department
Occupation name
researchmap researcher code
5000076449
researchmap agency
Okayama University of Science
Teacher Basic Information
Teacher Information
Full-Time Teacher
Other Affiliation
Academic Background
Career
Okayama University of Science/Graduate School of Engineering
Academic Society and Social Activity
日本生物工学会
Reward
Teaching Experiences
2024 専門英語ⅠＡ 岡山理科大学
2024 専門英語ⅠＢ 岡山理科大学
2024 専門英語１ 岡山理科大学
2024 生化学Ⅰ 岡山理科大学
2024 細胞生理学 岡山理科大学
Show All（39 Line）
2024 フレッシュマンゼミ 岡山理科大学
2024 コンプリヘンシブ化学システム演習Ⅲ 岡山理科大学
2024 卒業研究Ⅰ 岡山理科大学
2024 卒業研究Ⅱ 岡山理科大学
2024 特別研究Ⅰ 岡山理科大学
2024 特別研究Ⅱ 岡山理科大学
2024 特別研究Ⅲ 岡山理科大学
2023 応用化学における安全と倫理 岡山理科大学
2023 バイオ・応用化学実験Ⅳ 岡山理科大学
2023 バイオ・応用化学実験Ⅳ 岡山理科大学
2023 バイオ・応用化学実験Ⅲ 岡山理科大学
2023 バイオ・応用化学実験Ⅲ 岡山理科大学
2023 生化学Ⅱ 岡山理科大学
2023 発酵生産と機能性食品 岡山理科大学
2023 卒業研究Ⅱ 岡山理科大学
2023 専門英語ⅠＢ 岡山理科大学
2023 専門英語１ 岡山理科大学
2023 生化学Ⅰ 岡山理科大学
2023 フレッシュマンゼミ 岡山理科大学
2023 卒業研究Ⅰ 岡山理科大学
2023 卒業研究Ⅱ 岡山理科大学
2023 特別研究 岡山理科大学
2022 バイオ・応用化学における安全と倫理 岡山理科大学
2022 バイオ・応用化学実験Ⅳ 岡山理科大学
2022 発酵生産と機能性食品 岡山理科大学
2022 バイオ・応用化学ゼミナール 岡山理科大学
2022 卒業研究Ⅱ 岡山理科大学
2022 専門英語ⅠＢ (応化) 岡山理科大学
2022 フレッシュマンゼミⅡ 岡山理科大学
2022 フレッシュマンゼミⅠ 岡山理科大学
2022 フレッシュマンゼミ 岡山理科大学
2022 卒業研究Ⅰ 岡山理科大学
2022 卒業研究 岡山理科大学
2022 特別研究 岡山理科大学
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Thesis Advising
Teacher Activity Information
Field of Research
Life Science/Applied biochemistry
Research Keyword
extremophiles
evolution
enzyme
Hyperthermophile
Archaea
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タンパク質工学
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Academic Thesis
Insertion loop-mediated folding propagation governs efficient maturation of hyperthermophilic Tk-subtilisin at high temperatures./Ryo Uehara
Nanako Dan
Hiroshi Amesaka
Takuya Yoshizawa
Yuichi Koga
Shigenori Kanaya
Kazufumi Takano
Hiroyoshi Matsumura
Shun-Ichi Tanaka/FEBS letters
Effect of Nitrogen Gas Plasma Generated by a Fast-Pulsed Power Supply Using a Static Induction Thyristor on Scrapie Prion./Akikazu Sakudo
Yuichiro Imanishi
Azumi Hirata
Yuichi Koga
Hideharu Shintani/Pathogens (Basel, Switzerland)
Affinity shift of ATP upon glycerol binding to a glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1./Ryuta Hokao
Hiroyoshi Matsumura
Ryota Katsumi
Clement Angkawidjaja
Kazufumi Takano
Shigenori Kanaya
Yuichi Koga/Journal of bioscience and bioengineering
Characterization of Chinese hamster lung (CHL) cell lines, focusing on gene expression analysis/Rintaro Arishima
Noriko Yamano-Adachi
Yuichi Koga
Takeshi Omasa
Anaerobic glycerol-3-phosphate dehydrogenase complex from hyperthermophilic archaeon Thermococcus kodakarensis KOD1./Yuichi Koga
Kanako Konishi
Atsushi Kobayashi
Shigenori Kanaya
Kazufumi Takano/Journal of bioscience and bioengineering
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Secretion analysis of intracellular "difficult-to-express" immunoglobulin G (IgG) in Chinese hamster ovary (CHO) cells./Kohei Kaneyoshi
Kouki Kuroda
Keiji Uchiyama
Masayoshi Onitsuka
Noriko Yamano-Adachi
Yuichi Koga
Takeshi Omasa/Cytotechnology
Analysis of the immunoglobulin G (IgG) secretion efficiency in recombinant Chinese hamster ovary (CHO) cells by using Citrine-fusion IgG./Kohei Kaneyoshi
Noriko Yamano-Adachi
Yuichi Koga
Keiji Uchiyama
Takeshi Omasa/Cytotechnology
Analysis of intracellular IgG secretion in Chinese hamster ovary cells to improve IgG production./Kohei Kaneyoshi
Keiji Uchiyama
Masayoshi Onitsuka
Noriko Yamano
Yuichi Koga
Takeshi Omasa/Journal of Bioscience and Bioengineering
2018-11 Quantitative analysis of intracellular secretion of recombinant antibodies in CHO cells for establishment of high producers Kouki Kuroda
Kohei Kaneyoshi
Noriko Yamano
Yuichi Koga
Takeshi Omasa
2018-11 Characterization of CHO cells with disparate chromosome numbers and induction of artificial aneuploidy cells Noriko Yamano
Norichika Ogata
Yuan Shan Lai
Sho Tanaka
Wataru Tanaka
Yuichi Koga
Takeshi Omasa
Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain./Daichi Murata
Hiroyuki Okano
Clement Angkawidjaja
Masato Akutsu
Shun-Ichi Tanaka
Kenyu Kitahara
Takuya Yoshizawa
Hiroyoshi Matsumura
Yuji Kado
Eiichi Mizohata
Tsuyoshi Inoue
Satoshi Sano
Yuichi Koga
Shigenori Kanaya
Kazufumi Takano/Biochemistry
Hyperthermophilic Subtilisin-Like Proteases From Thermococcus kodakarensis/Uehara R
Takano K
Kanaya S
Koga Y/Biotechnology of Microbial Enzymes: Production, Biocatalysis and Industrial Applications
Effects of surfactant and a hyperthermostable protease on infectivity of Scrapie-infected mouse brain homogenate.
Proteolysis of Abnormal Prion Protein with a Thermostable Protease from a Hyper-Thermophilic Archaeon Thermococcus Kodakarensis Kod1/Koga Yuichi
Shimizu Nami
Sakudo Akikazu
Kanaya Shigenori/BIOPHYSICAL JOURNAL
Enzyme immobilization on gold/Fe-oxide composite nanoparticles using a methionine tag/Satoshi Seino
Kazuma Watanabe
Toshihiro Shikakura
Michika Abe
Takashi Nakagawa
Yuichi Koga
Takao A. Yamamoto/COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
Structural basis for salt-dependent folding of ribonuclease H1 from halophilic archaeon Halobacterium sp. NRC-1./Dong-Ju You
Nujarin Jongruja
Elias Tannous
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/Journal of structural biology
Calcium-independent opening of lid1 of a family I.3 lipase by a single Asp to Arg mutation at the calcium-binding site./M Cheng
C Angkawidjaja
Y Koga
S Kanaya/Protein engineering, design & selection : PEDS
Crystal structure and thermodynamic and kinetic stability of metagenome-derived LC-cutinase./Sintawee Sulaiman
Dong-Ju You
Eiko Kanaya
Yuichi Koga
Shigenori Kanaya/Biochemistry
Proteolysis of abnormal prion protein with a thermostable protease from Thermococcus kodakarensis KOD1./Yuichi Koga
Shun-ichi Tanaka
Akikazu Sakudo
Minoru Tobiume
Mutsuo Aranishi
Azumi Hirata
Kazufumi Takano
Kazuyoshi Ikuta
Shigenori Kanaya/Applied microbiology and biotechnology
Control the Functionality of Thermoresponsive Enzymes Immobilized onto Magnetic Nanoparticles by the Application of Alternating Magnetic Field./Seino S
Yoshida K
Shikakura T
Watnabe K
Koga Y
Nakagawa T
Yamamoto T. A/J. Mag. Soc. J.
Structural and mechanistic insights into the kynurenine aminotransferase-mediated excretion of kynurenic acid./Ken Okada
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/Journal of structural biology
Structure and stability of metagenome-derived glycoside hydrolase family 12 cellulase (LC-CelA) a homolog of Cel12A from Rhodothermus marinus./Hiroyuki Okano
Masashi Ozaki
Eiko Kanaya
Joong-Jae Kim
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/FEBS open bio
Formation of the high-affinity calcium binding site in pro-subtilisin E with the insertion sequence IS1 of pro-Tk-subtilisin./Ryo Uehara
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/Biochemistry
Increase in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domain./Kota Yuzaki
Yudai Sanda
Dong-Ju You
Ryo Uehara
Yuichi Koga
Shigenori Kanaya/Protein science : a publication of the Protein Society
Role of N-terminal extension of Bacillus stearothermophilus RNase H2 and C-terminal extension of Thermotoga maritima RNase H2./Etin-Diah Permanasari
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/The FEBS journal
Evolvability of thermophilic proteins from archaea and bacteria./Kazufumi Takano
Atsushi Aoi
Yuichi Koga
Shigenori Kanaya/Biochemistry
Crystal structure of metagenome-derived LC9-RNase H1 with atypical DEDN active site motif./Tri-Nhan Nguyen
Dong-Ju You
Eiko Kanaya
Yuichi Koga
Shigenori Kanaya/FEBS letters
Crystal structure of metagenome-derived LC11-RNase H1 in complex with RNA/DNA hybrid./Tri-Nhan Nguyen
Dong-Ju You
Hiroyuki Matsumoto
Eiko Kanaya
Yuichi Koga
Shigenori Kanaya/Journal of structural biology
Investigating the structural dependence of protein stabilization by amino acid substitution./Takashi Tadokoro
Hirotaka Kazama
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochemistry
Enzymatic activity of a subtilisin homolog, Tk-SP, from Thermococcus kodakarensis in detergents and its ability to degrade the abnormal prion protein./Azumi Hirata
Yuki Hori
Yuichi Koga
Jun Okada
Akikazu Sakudo
Kazuyoshi Ikuta
Shigenori Kanaya
Kazufumi Takano/BMC biotechnology
Accelerated maturation of Tk-subtilisin by a Leu→Pro mutation at the C-terminus of the propeptide, which reduces the binding of the propeptide to Tk-subtilisin./Ryo Uehara
Yasunori Ueda
Dong-Ju You
Yuichi Koga
Shigenori Kanaya/The FEBS journal
Heparanase localization during palatogenesis in mice/Hirata A
Katayama K
Tsuji T
Natsume N
Sugahara T
Koga Y
Takano K
Otsuki Y
Nakamura H/BioMed Research International
Slow unfolding pathway of hyperthermophilic Tk-RNase H2 examined by pulse proteolysis using the stable protease Tk-subtilisin./Jun Okada
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochemistry
Requirement of insertion sequence IS1 for thermal adaptation of Pro-Tk-subtilisin from hyperthermophilic archaeon./Ryo Uehara
Shun-Ichi Tanaka
Kazufumi Takano
Yuichi Koga
Shigenori Kanaya/Extremophiles : life under extreme conditions
Requirement of lid2 for interfacial activation of a family I.3 lipase with unique two lid structures./Maria Cheng
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/The FEBS journal
2012-09 2分子の単量体タンパク質を連結した人工タンパク質の活性と安定性 高宮 毅志
金谷 栄子
Clement Angkawidjaja
You Dong-Ju
高野 和文
古賀 雄一
金谷 茂則 日本生物工学会大会講演要旨集
Structure and stability of a thermostable carboxylesterase from the thermoacidophilic archaeon Sulfolobus tokodaii./Clement Angkawidjaja
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Flavobacterium compostarboris sp. nov., isolated from leaf-and-branch compost, and emended descriptions of Flavobacterium hercynium, Flavobacterium resistens and Flavobacterium johnsoniae./Joong-Jae Kim
Eiko Kanaya
Hang-Yeon Weon
Yuichi Koga
Kazufumi Takano
Peter F Dunfield
Soon-Wo Kwon
Shigenori Kanaya/International journal of systematic and evolutionary microbiology
Structure and characterization of RNase H3 from Aquifex aeolicus./Nujarin Jongruja
Dong-Ju You
Clement Angkawidjaja
Eiko Kanaya
Yuichi Koga
Shigenori Kanaya/The FEBS journal
Requirement of Ca(2+) ions for the hyperthermostability of Tk-subtilisin from Thermococcus kodakarensis./Ryo Uehara
Yuki Takeuchi
Shun-ichi Tanaka
Kazufumi Takano
Yuichi Koga
Shigenori Kanaya/Biochemistry
Degradation of abnormal prion protein by a hyper-stable protease/Kazufumi Takano
Yuki Hori
Azumi Hirata
Yuichi Koga
Akikazu Sakudo
Kazuyoshi Ikuta
Shigenori Kanaya/PRION
Activity, stability, and structure of metagenome-derived LC11-RNase H1, a homolog of Sulfolobus tokodaii RNase H1./Tri-Nhan Nguyen
Clement Angkawidjaja
Eiko Kanaya
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Protein science : a publication of the Protein Society
Role of polar and nonpolar residues at the active site for PPIase activity of FKBP22 from Shewanella sp. SIB1./Cahyo Budiman
Takashi Tadokoro
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/The FEBS journal
Isolation of a novel cutinase homolog with polyethylene terephthalate-degrading activity from leaf-branch compost by using a metagenomic approach./Sintawee Sulaiman
Saya Yamato
Eiko Kanaya
Joong-Jae Kim
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Applied and environmental microbiology
A dual role of divalent metal ions in catalysis and folding of RNase H1 from extreme halophilic archaeon Halobacterium sp. NRC-1./Elias Tannous
Koji Yokoyama
Dong-Ju You
Yuichi Koga
Shigenori Kanaya/FEBS open bio
Characteristic features of kynurenine aminotransferase allosterically regulated by (alpha)-ketoglutarate in cooperation with kynurenine./Ken Okada
Clement Angkawidjaja
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/PloS one
Crystal structure of N-domain of FKBP22 from Shewanella sp. SIB1: dimer dissociation by disruption of Val-Leu knot./Cahyo Budiman
Clement Angkawidjaja
Hideki Motoike
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Protein science : a publication of the Protein Society
2011-09 2つの同一ドメインを分子内に持つ人工タンパク質の安定性と活性 高宮 毅志
金谷 栄子
Angkawidjaja Clement
劉 東周
古賀 雄一
高野 和文
金谷 茂則 日本生化学会大会プログラム・講演要旨集
Thermococcus kodakaraensis由来のサブチリシン相同体であるTk-SPの安定性にCa2+イオンが果たす役割(Role of the Ca2+ ions for stability of subtilisin homologue, Tk-SP, from Thermococcus kadakaraensis)/Nitat Sinsereekul
Foophow Tita
Angkawidjaja Clement
Koga Yuichi
Takano Kazufumi
Kanaya Shigenori/日本生化学会大会プログラム・講演要旨集
Identification of the substrate binding site in the N-terminal TBP-like domain of RNase H3./Seiko Miyashita
Takashi Tadokoro
Clement Angkawidjaja
Dong-Ju You
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/FEBS letters
Flavobacterium banpakuense sp. nov., isolated from leaf-and-branch compost./Joong-Jae Kim
Hyun Mi Jin
Hyo Jung Lee
Che Ok Jeon
Eiko Kanaya
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/International journal of systematic and evolutionary microbiology
An alternative mature form of subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis identified in the presence of Ca2+./Nitat Sinsereekul
Tita Foophow
Mai Yamanouchi
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Importance of an extreme C-terminal motif of a family I.3 lipase for stability./K Kuwahara
C Angkawidjaja
Y Koga
K Takano
S Kanaya/Protein engineering, design & selection : PEDS
Laser-induced nucleation in protein crystallization: Local increase in protein concentration induced by femtosecond laser irradiation/Natsuko Iefuji
Ryota Murai
Mihoko Maruyama
Yoshinori Takahashi
Shigeru Sugiyama
Hiroaki Adachi
Hiroyoshi Matsumura
Satoshi Murakami
Tsuyoshi Inoue
Yusuke Mori
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF CRYSTAL GROWTH
Inhibition of chymotrypsin- and subtilisin-like serine proteases with Tk-serpin from hyperthermophilic archaeon Thermococcus kodakaraensis./Shun-ichi Tanaka
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochimica et biophysica acta
Stabilization by fusion to the C-terminus of hyperthermophile Sulfolobus tokodaii RNase HI: a possibility of protein stabilization tag./Kazufumi Takano
Tomohiro Okamoto
Jun Okada
Shun-ichi Tanaka
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/PloS one
FK506-Binding protein 22 from a psychrophilic bacterium, a cold shock-inducible peptidyl prolyl isomerase with the ability to assist in protein folding./Cahyo Budiman
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/International journal of molecular sciences
Crystal structure of stable protein CutA1 from psychrotrophic bacterium Shewanella sp. SIB1./Aya Sato
Sonoko Yokotani
Takashi Tadokoro
Shun-ichi Tanaka
Clement Angkawidjaja
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of synchrotron radiation
2010-12 LipBのATP結合ドメインの構造機能解析 岡野 啓志
中村 仁美
Angkawidjaja Clement
古賀 雄一
高野 和文
金谷 茂則 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集
The N-terminal hybrid binding domain of RNase HI from Thermotoga maritima is important for substrate binding and Mg2+-dependent activity./Nujarin Jongruja
Dong-Ju You
Eiko Kanaya
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI./Masaki Tanaka
Hyongi Chon
Clement Angkawidjaja
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Protein and peptide letters
Cloning of the RNase H genes from a metagenomic DNA library: identification of a new type 1 RNase H without a typical active-site motif./E Kanaya
T Sakabe
N T Nguyen
S Koikeda
Y Koga
K Takano
S Kanaya/Journal of applied microbiology
Crystal structure of a subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis: requirement of a C-terminal beta-jelly roll domain for hyperstability./Tita Foophow
Shun-ichi Tanaka
Clement Angkawidjaja
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of molecular biology
Evolution and thermodynamics of the slow unfolding of hyperstable monomeric proteins./Jun Okada
Tomohiro Okamoto
Atsushi Mukaiyama
Takashi Tadokoro
Dong-Ju You
Hyongi Chon
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/BMC evolutionary biology
X-ray crystallographic and MD simulation studies on the mechanism of interfacial activation of a family I.3 lipase with two lids./Clement Angkawidjaja
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of molecular biology
Degradation of Abnormal Prion Protein by a New Protease from a Hyperthermophile/Koga Yuichi
Tanaka Shun-ichi
Sakudo Akikazu
Ikuta Kazuyoshi
Takano Kazufumi
Kanaya Shigenori/PRION
Subtilisin-like serine protease from hyperthermophilic archaeon Thermococcus kodakaraensis with N- and C-terminal propeptides./T Foophow
S Tanaka
Y Koga
K Takano
S Kanaya/Protein engineering, design & selection : PEDS
Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin./Shun-ichi Tanaka
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of molecular biology
Requirement of a unique Ca(2+)-binding loop for folding of Tk-subtilisin from a hyperthermophilic archaeon./Yuki Takeuchi
Shun-ichi Tanaka
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochemistry
Engineering of monomeric FK506-binding protein 22 with peptidyl prolyl cis-trans isomerase. Importance of a V-shaped dimeric structure for binding to protein substrate./Cahyo Budiman
Keisuke Bando
Clement Angkawidjaja
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Proline effect on the thermostability and slow unfolding of a hyperthermophilic protein./Kazufumi Takano
Ryogo Higashi
Jun Okada
Atsushi Mukaiyama
Takashi Tadokoro
Yuichi Koga
Shigenori Kanaya/Journal of biochemistry
Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses./Muhammad S Rohman
Takashi Tadokoro
Clement Angkawidjaja
Yumi Abe
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Importance of the Ca2+-binding sites in the N-catalytic domain of a family I.3 lipase for activity and stability./K Kuwahara
C Angkawidjaja
H Matsumura
Y Koga
K Takano
S Kanaya/Protein engineering, design & selection : PEDS
Crystal structure of Tk-subtilisin folded without propeptide: requirement of propeptide for acceleration of folding./Shun-ichi Tanaka
Yuki Takeuchi
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/FEBS letters
Osmolyte effect on the stability and folding of a hyperthermophilic protein/Atsushi Mukaiyama
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation./Clement Angkawidjaja
Dong-ju You
Hiroyoshi Matsumura
Katsumasa Kuwahara
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/FEBS letters
Crystallization and preliminary X-ray diffraction study of glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakaraensis./Ryota Katsumi
Yuichi Koga
Dong-Ju You
Hiroyoshi Matsumura
Kazufumi Takano
Shigenori Kanaya/Acta crystallographica. Section F, Structural biology and crystallization communications
A hyperthermophilic protein acquires function at the cost of stability/Atsushi Mukaiyama
Mitsuru Haruki
Motonori Ota
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/BIOCHEMISTRY
Crystallization and preliminary crystallographic analysis of type 1 RNase H from the hyperthermophilic archaeon Sulfolobus tokodaii 7./Dong Ju You
Hyongi Chon
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Acta crystallographica. Section F, Structural biology and crystallization communications
Crystallization and preliminary X-ray diffraction study of active-site mutant of pro-Tk-subtilisin from a hyperthermophilic archaeon./Tanaka S
Saito K
Chon H
Matsumura H
Koga Y
Takano K
Kanaya S/Acta. Cryst. F
Extracellular secretion of Escherichia coli alkaline phosphatase with a C-terminal tag by type I secretion system: purification and biochemical characterization./C Angkawidjaja
K Kuwahara
K Omori
Y Koga
K Takano
S Kanaya/Protein engineering, design & selection : PEDS
Crystal structure of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3 at 2.20 angstrom resolution/H Chon
H Matsumura
Y Koga
K Takano
S Kanaya/PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Overproduction and preliminary crystallographic study of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3./Hyongi Chon
Hiroyoshi Matsumura
Shoko Shimizu
Nao Maeda
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Acta crystallographica. Section F, Structural biology and crystallization communications
Improvement in corrected QT dispersion by physical training and percutaneous transluminal coronary angioplasty in patients with recent myocardial infarction./S Kanaya
Y Nishiyama
H Maeda
K Tokuda
M Tanaka
K Hirano
Y Koga/Japanese circulation journal
Cloning of a ribonuclease HII gene from a hyperthermophilic archaeon: Purification and characterization of a recombinant enzyme./Haruki, M
Hayashi, K
Kouchi, T
Muroya, A
Koga, Y
Morikawa, M
Imanaka, T
Kanaya, S/J. Bacteriol.
Thermostable glycerol kinase from a hyperthermophilic archaeon: gene cloning and characterization of the recombinant enzyme./Y Koga
M Morikawa
M Haruki
H Nakamura
T Imanaka
S Kanaya/Protein engineering
[Rare case of ulcerative colitis and ankylosing spondylitis associated with aortitis and severe aortic valve insufficiency]./S kanaya
K Tokuda
S Tanaka
K Hirano
Y Koga
T Imaizumi
S Suzuki
S Aoyagi
S Kato
A Koga
H Ajisaka/Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
Aortic root replacement for Takayasu arteritis associated with ulcerative colitis and ankylosing spondylitis--report of a case./S Aoyagi
H Akashi
T Kawara
K Ishihara
A Tanaka
S Kanaya
Y Koga
R Ishikawa/Japanese circulation journal
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MISC
2016 超好熱古細菌Thermococcus kodakarensisglycerol-3-phosphate dehydrogenaseの機能解析 高野築
小林淳
小西香菜子
鈴木誠志
清野智史
大政健史
古賀雄一 日本農芸化学会大会講演要旨集(Web)
Crystal Structure of Glycoside Hydrolase Family 9 Endoglucanase with an N-Terminal Ig-Like Domain Isolated from Leaf-Branch Compost/Hiroyuki Okano
Eiko Kanaya
Masashi Ozaki
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/BIOPHYSICAL JOURNAL
超好熱菌由来プロテアーゼによるプリオン蛋白質分解の評価/清水七海
古賀雄一
作道章一
原英之
坂口末廣
金谷茂則/日本生化学会大会(Web)
超好熱菌由来プロテアーゼによるプリオンタンパク質分解物の評価/古賀雄一
清水七海
作道章一
原英之
坂口末廣
金谷茂則/日本生物工学会大会講演要旨集
ナノバイオ応用に適した金/酸化鉄複合ナノ粒子の合成とその評価/清野智史
古賀雄一
土井健史
中川晋作
中川貴
山本孝夫/電気学会全国大会講演論文集(CD-ROM)
Show All（140 Line）
プリオン病のサーベイランスと感染予防に関する調査研究 耐熱性プロテアーゼによる異常プリオン蛋白質の分解/古賀雄一
作道章一
平田あずみ/プリオン病のサーベイランスと感染予防に関する調査研究 平成25年度 総括・分担研究報告書
2P-086 Molecular mechanism of enantioselectivity inversion of lipaseKWI-56/Koga Yuichi
Hatanaka Akitomo
Fukuda Hiroyuki
Takano Kazufumi
Kanaya Shigenori
2013 金/酸化鉄磁性複合ナノ粒子への新規酵素固定化法 清野智史
渡邉和真
鹿倉敏裕
阿部美智果
中川貴
古賀雄一
山本孝夫 日本磁気学会学術講演概要集
2013 新規タグシステムを用いた金/酸化鉄複合ナノ粒子への酵素固定化法 渡邉和真
鹿倉敏裕
阿部美智果
清野智史
中川貴
古賀雄一
山本孝夫 ナノ学会会報
2013 新規タグシステムを用いた金/酸化鉄複合ナノ粒子への酵素固定化法 渡邉和真
鹿倉敏裕
阿部美智果
清野智史
中川貴
古賀雄一
山本孝夫 ナノ学会大会講演予稿集
プリオン病のサーベイランスと感染予防に関する調査研究 耐熱性プロテアーゼによるPrP
Sc
分解物の感染性の評価/古賀雄一
作道章一
平田あずみ
高野和文/プリオン病のサーベイランスと感染予防に関する調査研究 平成22-24年度 総合研究報告書
プリオン病のサーベイランスと感染予防に関する調査研究 耐熱性プロテアーゼによるプリオン分解/古賀雄一
作道章一
高野和文
平田あずみ/プリオン病のサーベイランスと感染予防に関する調査研究 平成24年度 総括・分担研究報告書
Rational Design of a Family I.3 Lipase Possessing Calcium-independent Activities/Maria Cheng
Clement Angkawidjaja
Yuichi Koga
Shigenori Kanaya/PROTEIN SCIENCE
3Hp02 Ca^<2+>-dependent stabilization mechanism of Tk-subtilisin from hyperthermophile/Uehara Ryo
Takeuchi Yuki
Tanaka Shun-ichi
Takano Kazufumi
Koga Yuichi
Kanaya Shigenori
2Cp14 Study of novel metagenome-derived esterase from leaf-and-branch compost/Okano Hiroyuki
Hong Xun
Yamato Saya
Kanaya Eiko
You Dong-Ju
Angkawidjaja Clement
Koga Yuichi
Kanaya Shigenori
2Cp10 Characterization of glycerol-3-phosphate dehydrogenase from Thermococcus kodakarensis KOD1/Koga Yuichi
Kobayashi Atsushi
You Dong-Ju
Sato Takaaki
Atomi Haruyuki
Kanaya Shigenori
2Cp24 Analysis of molecular mechanism for enantioselectivity of lipase from Burkholderia cepacia KWI-56/Hatanaka Akitomo
Fukuda Hiroyuki
You Dong-Ju
Angkawidjaja Clement
Koga Yuichi
Kanaya Shigenori
2Cp12 Evolvability of thermophilic proteins from Archaea and Bacteria/Aoi Atsushi
Angkawidjaja Clement
Koga Yuichi
Takano Kazufumi
Kanaya Shigenori
2Cp07 Characterization of Tk2168 from Thermococcus kodakarensis/Otaguro Haruki
Hirata Azumi
You Dong-Ju
Takano Kazufumi
Koga Yuichi
Kanaya Shigenori
2Cp08 Structural and functional studies of long- and short-type FKBPs from Thermococcus kodakarensis/Ando Yohei
Budiman Cahyo
Koga Yuichi
Kanaya Shigenori
4Cp21 Role of N- and C-terminal extensions of RNases H2 from thermophilic bacteria :/Permanasari Etin Diah
Jongruja Nujarin
Koga Yuichi
Kanaya Shigenori
4Cp20 Dual role of divalent metal ions in activating and replacing salt essential for folding of RNase H1 from a halophilic archaeon :/Tannous Elias
Yokoyama Koji
Koga Yuichi
Kanaya Shigenori
4Cp22 Stability of the active-site mutants of Tk-SP from hyperthermophilic archaeon/Abe Kazumasa
Koga Yuichi
Kanaya Shigenori
4Ca13 Improvement of maturation rate of Tk-subtilisin by propeptide engineering/Yuzaki Kota
Uehara Rryo
Sanda Yudai
Koga Yuichi
Kanaya Shigenori
4Cp18 Crystal structure of a metagenome-derived homolog of Sulfolobus tokodaii RNase H1 :/Nguyen Tri-Nhan
Angkawidjaja Clement
Matsumoto Hiroyuki
You Dong-Ju
Koga Yuichi
Kanaya Shigenori
2012 磁性ナノ粒子による誘導加熱を用いた酵素活性のON/OFF制御に関する新規技術 鹿倉敏裕
吉田一成
阿部美智果
渡邉和真
清野智史
中川貴
山本孝夫
古賀雄一
金谷茂則 日本生物工学会大会講演要旨集
プリオン病のサーベイランスと感染予防に関する調査研究 耐熱性プロテアーゼによるプリオン分解/古賀雄一
作道章一
高野和文
平田あずみ/プリオン病のサーベイランスと感染予防に関する調査研究 平成23年度 総括・分担研究報告書
Tk‐subtilisinによる異常型プリオンタンパク質分解効果の生物学的検討/平田あずみ
古賀雄一
田中俊一
作道章一
生田和良
金谷茂則
高野和文/日本生体防御学会学術総会講演抄録集
異常プリオン蛋白質(PrP
Sc
)の超好熱菌由来プロテアーゼによる分解/古賀雄一
田中俊一
作道章一
高野和文
金谷茂則/日本防菌防ばい学会年次大会要旨集
金/酸化鉄磁性複合ナノ粒子を用いたタンパク質の精製/清野智史
澤祐司
中川貴
古賀雄一
岡田欣晃
土井健史
中川晋作
山本孝夫/日本磁気学会学術講演概要集
超好熱菌由来プロテアーゼによる異常プリオン蛋白質分解/古賀雄一
田中俊一
作道章一
高野和文
金谷茂則/日本生物工学会大会講演要旨集
金/酸化鉄複合ナノ粒子のタンパク質吸着性能の評価/清野智史
澤祐司
舛賀康祐
中川貴
古賀雄一
小林望
岡田欣晃
土井健史
山本孝夫/ナノ学会大会講演予稿集
タンパク質立体構造の安定性に関与する「部位とアミノ酸残基」の関係/風間洋隆
田所高志
古賀雄一
高野和文
金谷茂則/生化学
高度好塩菌由来RNase HIの高塩環境適応機構に関する研究/横山光士
田所高志
金谷栄子
古賀雄一
高野和文
金谷茂則/生化学
低温菌Shewanella oneidensis MR‐1由来CutA1の安定性解析/佐藤彩
田所高志
古賀雄一
高野和文
金谷茂則/生化学
Structural and functional characterization of glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1/Ryuta Hokao
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF BIOSCIENCE AND BIOENGINEERING
大腸菌リボヌクレアーゼHI5重置換熱安定化変異体の立体構造および熱力学的解析/春木満
田中雅紀
茂木毅彦
田所高志
古賀雄一
高野和文
金谷茂則/化学系学協会東北大会プログラムおよび講演予稿集
Arg142とPhe197はシュワネラ種SIB1由来FKBP22のプロリルイソメラーゼ活性に重要である(Importance of Arg142 and Phe197 for Prolyl Isomerase Activity of FKBP22 from Shewanella sp. SIB1)/ブディマン・チャヒヨ
田所 高志
アンカウィジャヤ・クレメン
古賀 雄一
高野 和文
金谷 茂則/日本生化学会大会プログラム・講演要旨集
2009 金/酸化鉄複合ナノ粒子の磁気イムノクロマトへの応用 渡邉慎也
清野智史
古賀雄一
安森美穂
山本孝夫 ナノ学会大会講演予稿集
Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII/Muhammad S. Rohman
Yuichi Koga
Kazufumi Takano
Hyongi Chon
Robert J. Crouch
Shigenori Kanaya/FEBS JOURNAL
Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII./Muhammad S Rohman
Yuichi Koga
Kazufumi Takano
Hyongi Chon
Robert J Crouch
Shigenori Kanaya/The FEBS journal
Remarkable stabilization of a psychrotrophic RNase HI by a combination of thermostabilizing mutations identified by the suppressor mutation method./Takashi Tadokoro
Kyoko Matsushita
Yumi Abe
Muhammad Saifur Rohman
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochemistry
Remarkable stabilization of a psychrotrophic RNase HI by a combination of thermostabilizing mutations identified by the suppressor mutation method/Takashi Tadokoro
Kyoko Matsushita
Yumi Abe
Muhammad Saifur Rohman
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/BIOCHEMISTRY
Crystal structure of highly thermostable glycerol kinase from a hyperthermophilic archaeon in a dimeric form/Yuichi Koga
Ryota Katsumi
Dong-Ju You
Hiroyoshi Matsumura
Kazufumi Takano
Shigenori Kanaya/FEBS JOURNAL
Crystal structure of highly thermostable glycerol kinase from a hyperthermophilic archaeon in a dimeric form./Yuichi Koga
Ryota Katsumi
Dong-Ju You
Hiroyoshi Matsumura
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Hydrophobic effect on the stability and folding of a hyperthermophilic protein./Hongju Dong
Atsushi Mukaiyama
Takashi Tadokoro
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of molecular biology
Hydrophobic effect on the stability and folding of a hyperthermophilic protein/Hongju Dong
Atsushi Mukaiyama
Takashi Tadokoro
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF MOLECULAR BIOLOGY
Osmolyte effect on the stability and folding of a hyperthermophilic protein/Atsushi Mukaiyama
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Osmolyte effect on the stability and folding of a hyperthermophilic protein./Atsushi Mukaiyama
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Proteins
2008 「酵素の機能改変における結晶構造の役割」、タンパク質結晶の新展開、 シーエムシー出版
2008 新規金-酸化鉄複合磁性ナノ粒子を利用したOBOC(One-Bead One-Compound)ペプチドライブラリーの開発 古賀雄一
桑原将行
藤内謙光
高野和文
清野智史
金谷茂則 日本生物工学会大会講演要旨集
Requirement of left-handed glycine residue for high stability of the Tk-subtilisin propeptide as revealed by mutational and crystallographic analyses./Marian A Pulido
Shun-ichi Tanaka
Chutima Sringiew
Dong-Ju You
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of molecular biology
Requirement of left-handed glycine residue for high stability of the Tk-subtilisin propeptide as revealed by mutational and crystallographic analyses/Marian A. Pulido
Shun-ichi Tanaka
Chutima Sringiew
Dong-Ju You
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF MOLECULAR BIOLOGY
Structural and thermodynamic analyses of Escherichia coli RNase HI variant with quintuple thermostabilizing mutations/Mitsuru Haruki
Masaki Tanaka
Takehiko Motegi
Takashi Tadokoro
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/FEBS JOURNAL
Structural and thermodynamic analyses of Escherichia coli RNase HI variant with quintuple thermostabilizing mutations./Mitsuru Haruki
Masaki Tanaka
Takehiko Motegi
Takashi Tadokoro
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Crystal structure of type 1 ribonuclease H from hyperthermophilic archaeon Sulfolobus tokodaii: role of arginine 118 and C-terminal anchoring./Dong-Ju You
Hyongi Chon
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochemistry
Protein thermostabilization requires a fine-tuned placement of surface-charged residues./Dong-Ju You
Satoshi Fukuchi
Ken Nishikawa
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of biochemistry
Protein thermostabilization requires a fine-tuned placement of surface-charged residues/Dong-Ju You
Satoshi Fukuchi
Ken Nishikawa
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF BIOCHEMISTRY
Crystal structure of type 1 ribonuclease H from hyperthermophilic Archaeon Sulfolobus tokodaii: Role of arginine 118 and C-terminal anchoring/Dong-Ju You
Hyongi Chons
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/BIOCHEMISTRY
Four new crystal structures of Tk-subtilisin in unautoprocessed, autoprocessed and mature forms: insight into structural changes during maturation./Shun-Ichi Tanaka
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of molecular biology
Four new crystal structures of Tk-subtilisin in unautoprocessed, autoprocessed and mature forms: Insight into structural changes during maturation/Shun-ichi Tanaka
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF MOLECULAR BIOLOGY
Conformational contagion in a protein: structural properties of a chameleon sequence./Kazufumi Takano
Yoshiaki Katagiri
Atsushi Mukaiyama
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Shigenori Kanaya/Proteins
低温菌由来シャペロンを利用した蛋白質の可溶化発現/西尾明夏
古賀雄一
田所高志
大谷直人
高野和文
金谷茂則/日本生物工学会大会講演要旨集
RNase HIIIの基質結合に関与するアミノ酸残基の同定/宮下聖子
田所高志
古賀雄一
高野和文
金谷茂則/日本生物工学会大会講演要旨集
Conformational contagion in a protein: Structural properties of a chameleon sequence/Kazufumi Takano
Yoshiaki Katagiri
Atsushi Mukaiyama
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Shigenori Kanaya/PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Identification of the gene encoding a type 1 RNase H with an N-terminal double-stranded RNA binding domain from a psychrotrophic bacterium/Takashi Tadokoro
Hyongi Chon
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/FEBS JOURNAL
Identification of the gene encoding a type 1 RNase H with an N-terminal double-stranded RNA binding domain from a psychrotrophic bacterium./Takashi Tadokoro
Hyongi Chon
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Structural, thermodynamic, and mutational analyses of a psychrotrophic RNase HI./Takashi Tadokoro
Dong-Ju You
Yumi Abe
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochemistry
Structural, thermodynamic, and mutational analyses of a psychrotrophic RNase HI/Takashi Tadokoro
Dong-Ju You
Yumi Abe
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/BIOCHEMISTRY
サプレッサー変異法による低温蛋白質の安定化/田所高志
松下恭子
古賀雄一
高野和文
金谷茂則/日本蛋白質科学会年会プログラム・要旨集
Crystal structure of unautoprocessed precursor of subtilisin from a hyperthermophilic archaeon: evidence for Ca2+-induced folding./Shun-ichi Tanaka
Kenji Saito
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The Journal of biological chemistry
Extracellular overproduction and preliminary crystallographic analysis of a family I.3 lipase./Clement Angkawidjaja
Dong-Ju You
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Acta crystallographica. Section F, Structural biology and crystallization communications
Crystal structure of unautoprocessed precursor of subtilisin from a hyperthermophilic Archaeon - Evidence for Ca2+-induced folding/Shun-ichi Tanaka
Kenji Saito
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF BIOLOGICAL CHEMISTRY
Directed evolution of Tk-subtilisin from a hyperthermophilic archaeon: identification of a single amino acid substitution responsible for low-temperature adaptation./M A Pulido
Y Koga
K Takano
S Kanaya/Protein engineering, design & selection : PEDS
Directed evolution of Tk-subtilisin from a hyperthermophilic archaeon: identification of a single amino acid substitution responsible for low-temperature adaptation/M. A. Pulido
Y. Koga
K. Takano
S. Kanaya/PROTEIN ENGINEERING DESIGN & SELECTION
Extracellular overproduction and preliminary crystallographic analysis of a family I.3 lipase/Clement Angkawidjaja
Dong-Ju You
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Acta Crystallographica Section F: Structural Biology and Crystallization Communications
Crystallization and preliminary X-ray diffraction study of glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakaraensis/Ryota Katsumi
Yuichi Koga
Dong-Ju You
Hiroyoshi Matsumura
Kazufumi Takano
Shigenori Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
Crystallization and preliminary X-ray diffraction study of glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakaraensis/Ryota Katsumi
Yuichi Koga
Dong-Ju You
Hiroyoshi Matsumura
Kazufumi Takano
Shigenori Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
2007 “Creation of novel enantioselective lipases by SIMPLEX”In vitro transcription and translatio protocols, 2nd edition, Methods in molecular biology Humana Press
Crystal structure of amyloid beta fragment/K. Takano
Y. Takeda
D. -J. You
A. Mukaiyama
H. Matsumura
Y. Koga
S. Kanaya/NEW TRENDS IN ALZHEIMER AND PARKINSON RELATED DISORDERS: ADPD 2007
2007 Extracellular overproduction and preliminary crystallographic analysis of family I.3 lipase Acta Crysatallographica Section F
"Creation of novel enantioselective lipases by SIMPLEX" In vitro transcription and translatio protocols, 2nd edition, Methods in molecular biology/Humana Press
Crystal structure of amyloid beta fragment/K. Takano
Y. Takeda
D. -J. You
A. Mukaiyama
H. Matsumura
Y. Koga
S. Kanaya/NEW TRENDS IN ALZHEIMER AND PARKINSON RELATED DISORDERS: ADPD 2007
Extracellular overproduction and preliminary crystallographic analysis of family I.3 lipase/Acta Crysatallographica Section F
A hyperthermophilic protein acquires function at the cost of stability./Atsushi Mukaiyama
Mitsuru Haruki
Motonori Ota
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Biochemistry
Application of femtosecond laser ablation for detaching grown protein crystals from glass capillary tube/Masafumi Kashii
Ryo Fujisawa
Hiroaki Adachi
Yusuke Mori
Takatomo Sasaki
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya
Hiroyoshi Matsumura
Tsuyoshi Inoue
Satoshi Murakami
Kazuomi Sugamoto
Hideki Yoshikawa/JOURNAL OF BIOSCIENCE AND BIOENGINEERING
A hyperthermophilic protein acquires function at the cost of stability/Atsushi Mukaiyama
Mitsuru Haruki
Motonori Ota
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/BIOCHEMISTRY
Application of femtosecond laser ablation for detaching grown protein crystals from glass capillary tube./Masafumi Kashii
Ryo Fujisawa
Hiroaki Adachi
Yusuke Mori
Takatomo Sasaki
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya
Hiroyoshi Matsumura
Tsuyoshi Inoue
Satoshi Murakami
Kazuomi Sugamoto
Hideki Yoshikawa/Journal of bioscience and bioengineering
Crystallization and preliminary X-ray diffraction study of an active-site mutant of pro-Tk-subtilisin from a hyperthermophilic archaeon./Shun-ichi Tanaka
Kenji Saito
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Acta crystallographica. Section F, Structural biology and crystallization communications
Crystallization and preliminary X-ray diffraction study of an active-site mutant of pro-Tk-subtilisin from a hyperthermophilic archaeon/Shun-ichi Tanaka
Kenji Saito
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
蛋白質の構造‐配列‐安定性相関に関する研究/松下恭子
田所高志
古賀雄一
高野和文
金谷茂則/日本生物工学会大会講演要旨集
Crystallization and preliminary crystallographic analysis of type 1 RNase H from the hyperthermophilic archaeon Sulfolobus tokodaii 7/Dong-Ju You
Hyongi Chon
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
Crystallization and preliminary crystallographic analysis of type 1 RNase H from the hyperthermophilic archaeon Sulfolobus tokodaii 7/Dong-Ju You
Hyongi Chon
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
Effect of ultrasonic irradiation on protein crystallization/Keisuke Kakinouchi
Hiroaki Adachi
Hiroyoshi Matsumura
Tsuyoshi Inoue
Satoshi Murakami
Yusuke Mori
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF CRYSTAL GROWTH
Extracellular secretion of Escherichia coli alkaline phosphatase with a C-terminal tag by type I secretion system: purification and biochemical characterization/C. Angkawidjaja
K. Kuwahara
K. Omori
Y. Koga
K. Takano
S. Kanaya/PROTEIN ENGINEERING DESIGN & SELECTION
Effect of ultrasonic irradiation on protein crystallization/Keisuke Kakinouchi
Hiroaki Adachi
Hiroyoshi Matsumura
Tsuyoshi Inoue
Satoshi Murakami
Yusuke Mori
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/JOURNAL OF CRYSTAL GROWTH
Extracellular secretion of Escherichia coli alkaline phosphatase with a C-terminal tag by type I secretion system: purification and biochemical characterization/C. Angkawidjaja
K. Kuwahara
K. Omori
Y. Koga
K. Takano
S. Kanaya/PROTEIN ENGINEERING DESIGN & SELECTION
Ca2+-dependent maturation of subtilisin from a hyperthermophilic archaeon, Thermococcus kodakaraensis: the propeptide is a potent inhibitor of the mature domain but is not required for its folding./Marian Pulido
Kenji Saito
Shun-Ichi Tanaka
Yuichi Koga
Masaaki Morikawa
Kazufumi Takano
Shigenori Kanaya/Applied and environmental microbiology
Ca2+-dependent maturation of subtilisin from a hyperthermophilic archaeon, Thermococcus kodakaraensis: the propeptide is a potent inhibitor of the mature domain but is not required for its folding/M Pulido
K Saito
SI Tanaka
Y Koga
M Morikawa
K Takano
S Kanaya/APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Identification of RNase HII from psychrotrophic bacterium, Shewanella sp SIB1 as a high-activity type RNase H/H Chon
T Tadokoro
N Ohtani
Y Koga
K Takano
S Kanaya/FEBS JOURNAL
Identification of RNase HII from psychrotrophic bacterium, Shewanella sp. SIB1 as a high-activity type RNase H./Hyongi Chon
Takashi Tadokoro
Naoto Ohtani
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/The FEBS journal
Amyloidogenecity and pitrilysin sensitivity of a lysine-free derivative of amyloid beta-peptide cleaved from a recombinant fusion protein./Joel C Cornista
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of biotechnology
Amyloidogenecity and pitrilysin sensitivity of a lysine-free derivative of amyloid beta-peptide cleaved from a recombinant fusion protein/JC Cornista
Y Koga
K Takano
S Kanaya/JOURNAL OF BIOTECHNOLOGY
Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: A new type 2 RNase H with TBP-like substrate-binding domain at the N terminus/Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of Molecular Biology
Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus./Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Journal of molecular biology
Structure of amyloid beta fragments in aqueous environments./Kazufumi Takano
Shuji Endo
Atsushi Mukaiyama
Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Shigenori Kanaya/The FEBS journal
2006 低温菌由来タンパク質の利用 実用産業情報
Structure of amyloid beta fragments in aqueous environments/K Takano
S Endo
A Mukaiyama
H Chon
H Matsumura
Y Koga
S Kanaya/FEBS JOURNAL
Crystal structure of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3 at 2.20 Å resolution/Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Proteins: Structure, Function and Genetics
Crystal structure of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3 at 2.20 A resolution./Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Proteins
Binding analysis of a psychrotrophic FKBP22 to a folding intermediate of protein using surface plasmon resonance./Yutaka Suzuki
Ohnmar Ye Win
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/FEBS letters
Importance of a repetitive nine-residue sequence motif for intracellular stability and functional structure of a family I.3 lipase./Clement Angkawidjaja
Aditya Paul
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/FEBS letters
Novel strategy for protein exploration: High-throughput screening. assisted with fuzzy neural network/R Kato
H Nakano
H Konishi
K Kato
Y Koga
T Yamane
T Kobayashi
H Honda/JOURNAL OF MOLECULAR BIOLOGY
Novel strategy for protein exploration: High-throughput screening. assisted with fuzzy neural network/R Kato
H Nakano
H Konishi
K Kato
Y Koga
T Yamane
T Kobayashi
H Honda/JOURNAL OF MOLECULAR BIOLOGY
Mutational and crystallographic studies of RNase HIII from Bacillus stearothermophilus: importance of N-terminal domain on substrate binding/H Chon
K Takano
H Matsumura
Y Koga
S Kanaya/FEBS JOURNAL
Protein crystal growth using laser-processed seed crystals/K Takeuchi
H Kitano
H Adachi
Y Mori
T Sasaki
H Matsumura
T Inoue
S Murakami
M Doi
Y Koga
K Takano
S Kanaya/JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS BRIEF COMMUNICATIONS & REVIEW PAPERS
Protein crystal growth using laser-processed seed crystals/K Takeuchi
H Kitano
H Adachi
Y Mori
T Sasaki
H Matsumura
T Inoue
S Murakami
M Doi
Y Koga
K Takano
S Kanaya/JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS BRIEF COMMUNICATIONS & REVIEW PAPERS
Crystallization and preliminary X-ray diffraction study of thermostable RNase HIII from Bacillus stearothermophilus/H Chon
H Matsumura
Y Koga
K Takano
S Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
Overproduction and preliminary crystallographic study of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3/H Chon
H Matsumura
S Shimizu
N Maeda
Y Koga
K Takano
S Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
Crystallization and preliminary X-ray diffraction study of thermostable RNase HIII from Bacillus stearothermophilus./Hyongi Chon
Hiroyoshi Matsumura
Yuichi Koga
Kazufumi Takano
Shigenori Kanaya/Acta crystallographica. Section F, Structural biology and crystallization communications
Overproduction and preliminary crystallographic study of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3/H Chon
H Matsumura
S Shimizu
N Maeda
Y Koga
K Takano
S Kanaya/ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
Binding analysis of a psychrotrophic FKBP22 to a folding intermediate of protein using surface plasmon resonance/FEBS Let.
Importance of a repetitive nine-residue sequence motif for intracellular stability and functional structure of a family I.3 lipase/FEBS Letters
Inverting enantioselectivity of Burkholderia cepacia KWI-56 lipase by combinatorial mutation and high-throughput screening using single-molecule PCR and in vitro expression/Y Koga
K Kato
H Nakano
T Yamane/JOURNAL OF MOLECULAR BIOLOGY
Inverting enantioselectivity of Burkholderia cepacia KWI-56 lipase by combinatorial mutation and high-throughput screening using single-molecule PCR and in vitro expression/Y Koga
K Kato
H Nakano
T Yamane/JOURNAL OF MOLECULAR BIOLOGY
2003 コンビナトリアルバイオエンジニアリング（第20章 無細胞タンパク質合成系によるタンパク質工学） 化学同人
In vitro construction and screening of a Burkholderia cepacia lipase library using single-molecule PCR and cell-free protein synthesis/Y Koga
K Kobayashi
JH Yang
H Nakano
T Yamane/JOURNAL OF BIOSCIENCE AND BIOENGINEERING
In vitro construction and screening of a Burkholderia cepacia lipase library using single-molecule PCR and cell-free protein synthesis/Y Koga
K Kobayashi
JH Yang
H Nakano
T Yamane/JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Modifying the chain-length selectivity of the lipase from Burkholderia cepacia KWI-56 through in vitro combinatorial mutagenesis in the substrate-binding site/J Yang
Y Koga
H Nakano
T Yamane/PROTEIN ENGINEERING
Modifying the chain-length selectivity of the lipase from Burkholderia cepacia KWI-56 through in vitro combinatorial mutagenesis in the substrate-binding site/J Yang
Y Koga
H Nakano
T Yamane/PROTEIN ENGINEERING
Active subtilisin-like protease from a hyperthermophilic archaeon in a form with a putative prosequence./Y Kannan
Y Koga
Y Inoue
M Haruki
M Takagi
T Imanaka
M Morikawa
S Kanaya/Applied and environmental microbiology
Stabilities of chimeras of hyperthermophilic and mesophilic glycerol kinases constructed by DNA shuffling/Y Koga
M Haruki
M Morikawa
S Kanaya/JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Active subtilisin-like protease from a hyperthermophilic archaeon in a form with a putative prosequence/Y Kannan
Y Koga
Y Inoue
M Haruki
M Takagi
T Imanaka
M Morikawa
S Kanaya/APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2001 Subtilisin-like protease from a hyperthermophilic archaeon Bio Thailand 2001
Stabilities of chimeras of hyperthermophilic and mesophilic glycerol kinases constructed by DNA shuffling./Y Koga
M Haruki
M Morikawa
S Kanaya/Journal of bioscience and bioengineering
Subtilisin-like protease from a hyperthermophilic archaeon/Bio Thailand 2001
Gene cloning and characterization of recombinant RNase HII from a hyperthermophilic archaeon./M Haruki
K Hayashi
T Kochi
A Muroya
Y Koga
M Morikawa
T Imanaka
S Kanaya/Journal of bacteriology
1998 Thermostable glycerol kinase from a hyperthermophilic archaeon: gene cloning and characterization of the recombinant enzyme Protein Eng. 11, 1219-1227
Gene cloning and characterization of recombinant ribonuclease HII from a hyperthermophilic archaeon/J. Bacteriol. 180, 6207-6214
Thermostable glycerol kinase from a hyperthermophilic archaeon: gene cloning and characterization of the recombinant enzyme/Protein Eng. 11, 1219-1227
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Bibliography
2017-07 “Hyperthermophilic subtilisin-like protease from Themococcus kodakarensis.” （分担執筆）“Biotechnology of Microbial Enzymes, production, biocatalysis and industrial applications” Uehara R
Takano K
Kanaya S
Koga Y 共著 Academic Press
2016-11 「地方創生に関わる生物工学のとりくみ地域生物資源産業化事例集」 古賀雄一
櫻谷英治
大政健史 共著 三恵社
Conference
Works
2008 酵素のキラル分子認識機構の熱力学的解析
2008 金磁性ナノ粒子をコア技術とする医療・診断・分析ツールの実用化
2007 酵素のキラル分子認識機構の熱力学的解析
2007 金磁性ナノ粒子をコア技術とする医療・診断・分析ツールの実用化
2006 金磁性ナノ粒子をコア技術とする医療・診断・分析ツールの実用化
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2004 海外先進教育研究推進プログラム
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Competitive research funds
Development of binding scaffold with a protein from a hyperthermophilic archaeon/Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Analysis of abnormal prion protein core structure by proteolysis at high temperature/Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Development of a technology to degrade, remove or process persistent proteins with enzymes/Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
Comprehensive analysis of glycerol metabolism in archaea/Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research
Studies on glycerol metabolism of hyperthermophilic arhaea/Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
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Elucidation of the maturation mechanism of subtilisins from hyperthermophiles and development of their potential use/Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
Thermodynamic analysis of chiral molecule recognition of enzymes/Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
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Contributions
Patents
Other Research Achivements
古賀雄一
Educational Improvement Achievement
On-campus Conference Management
2007 電子情報編集委員
Off-Campus Operations
Off-campus Conference Management
Social Contribution
